(NaturalHealth365)  Prostate cancer is the most common cancer in men.  More than 299,000 new cases of prostate cancer will be diagnosed in 2024 alone.

A new study published in Nutrients reveals environmental endocrine disruptors, including BPA (Bisphenol A) chemicals, are tied to a heightened risk of prostate cancer.

Elevated BPA levels have a causal relationship with a higher incidence of prostate cancer

The study found that higher exposure to BPA chemicals in men was associated with an increased risk of developing prostate cancer.  Researchers utilized data from the National Health and Nutrition Examination Survey (NHANES) collected between 2003 and 2012 and analyzed several factors, including BPA levels, prostate-specific antigen (PSA) concentration, medical history, and sociodemographic information.

Sociodemographic data considered in the study included:

• Body mass index (BMI)
• Poverty income ratio (PIR)
• Race and ethnicity
• Smoking status
• Cholesterol levels

Statistical analysis revealed a positive correlation between BPA exposure and prostate cancer risk.  This is likely due to BPA’s interaction with estrogen receptor-α, a hormone expressed in the prostate gland, which may play a role in the development of prostate cancer.

Defining prostate cancer risk through quantification

According to the Centers for Disease Control and Prevention (CDC), a PSA level of 4 ng/mL is considered a threshold for prostate cancer risk.  Levels below 4 ng/mL are associated with low cancer risk, while readings above 4 ng/mL indicate a higher risk.

From the nearly 54,000 participants in NHANES, 2,738 men met the study’s inclusion criteria.  The analysis identified a correlation between PSA and BPA levels, showing that for each unit increase in BPA concentration, there was a 2.760 ng/mL rise in PSA.

Further data showed that men classified as high-risk for prostate cancer had a 42.5% to 72% increased likelihood of developing the disease with each additional unit of BPA concentration.  A single unit increase in urinary BPA levels corresponded to a 2.760 ng/mL spike in PSA, reinforcing the connection between BPA exposure and elevated PSA levels, which may lead to the development of prostate cancer.

Additional analysis of a subgroup revealed that individuals aged 75 and older had an even higher risk.  Those with hypertension also showed an increased risk of prostate cancer, which escalated alongside rising BPA concentrations.

The positive association between BPA and PSA levels has a key cutoff point

Research has identified a significant inflection point in the relationship between BPA concentration and PSA levels at 4.46 ng/mL.  The positive correlation between BPA exposure and PSA levels is notably stronger at this specific threshold, particularly in older American males.  This cutoff point marks a critical value where the risk of elevated PSA, and potentially prostate cancer, becomes more pronounced with increasing BPA levels.

This finding is important because previous studies may have overlooked such specific benchmarks.  Medical professionals will likely adopt the 4.46 ng/mL cutoff as a valuable reference for prostate cancer screenings.  This could improve early detection, especially as BPA exposure becomes a recognized factor in prostate cancer risk.

Solutions to reduce your BPA exposure

BPA (Bisphenol A) is widely present in many everyday products, making it impossible to avoid them completely.  However, there are effective ways to significantly reduce your exposure to this harmful chemical, particularly for men concerned about the link between BPA and prostate health.

1. Minimize plastic use

Reduce or eliminate your use of plastic products, especially those that come into contact with food.  BPA is commonly found in plastic containers, water bottles, and packaging materials.  Opt for BPA-free or non-plastic alternatives such as glass, stainless steel, or ceramic.

2. Transfer food to non-plastic containers

After shopping, transfer foods from plastic or canned packaging into non-plastic containers.  Cans often have BPA in their lining, so moving food to safer storage options, like glass containers, reduces potential BPA leaching.

3. Avoid heating food in plastic

Never microwave or heat up a food in plastic containers, as heat can cause BPA to leach into the food.  Instead, use alternative containers like glass or ceramic.  Plus, as a ‘side note,’ don’t use a microwave – which damages the quality of your food.

4. Limit canned foods

BPA is often used in the lining of canned foods, so try to reduce the consumption of canned goods.  Choose fresh or frozen foods whenever possible, and look for brands with BPA-free packaging.

5. Use BPA-free water bottles and tableware

Replace plastic water bottles with BPA-free versions, or use stainless steel or glass bottles.  Similarly, switch to BPA-free plates and utensils to further limit exposure.

6. Say no to sales receipts

Many thermal paper receipts contain BPA, which can be absorbed through the skin.  If possible, decline printed receipts or use digital receipts as an alternative.

7. Be mindful of other sources

BPA is also found in protective eyewear, dental sealants, and personal care products.  Be conscious of the materials you come into contact with and seek BPA-free alternatives where applicable.

By following these steps, you can significantly reduce your exposure to BPA and minimize the health risks associated with these endocrine-disrupting chemicals.

Sources for this article include:

MDPI.com
News-medical.net
Zerocancer.org